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A potential new HIV treatment; Algerians protest against an aging president seeking a fifth term.
Gene mutation that causes HIV resistance
- A cure for HIV has been a coveted dream – and researchers can be one step closer now, according to a new paper. A patient in London with HIV who also had Hodgkin's lymphoma received a stem cell transplant containing a gene mutation for HIV resistance and has apparently been HIV-free since September 2017. [Vox / Julia Belluz]
- A person has previously been "cured" by HIV. Timothy Ray Brown, "Berlin Patient", has been HIV-free since 2007 when doctors used a similar bone marrow transplant treatment. The London patient must be relieved for 18 months in order to be considered cured. A complete cure means that the mutated CCR5 protein in the transplanted cells will protect against HIV infecting any of its T cells and replacing existing cells that are not immune. [Live Science / Rachael Rettner]
- Bone marrow transplants are not likely to be a widespread cure for HIV, but the paper suggests opportunities for gene therapy, which has been tested but has not yet been successful. [NYT / Apoorva Mandavilli]
- Since most people with HIV do not have cancer, their treatment would not require radiation and chemotherapy that patients in London and Berlin received before the bone marrow transplant. [Nature / Matthew Warren]
- Advances in HIV treatment have made the disease a chronic disease rather than a death sentence. People with HIV and people without HIV live about as much time. However, there is great inequality in who gets access to HIV treatment. [The Conversation / Allison Webel]
- The London patient now joins an exclusive club of two. When Brown was profiled in 2011, he said that his two stem cell transplants left him with neurological damage – a reminder that even a "miracle treatment" is rarely uncomplicated. [NYMag / Tina Rosenberg]
Algerians say their presidential concessions are not enough
- Algeria is in the midst of its biggest protests since the Arab Spring 2011, a movement that wants the country's president, Abdelaziz Bouteflika, almost paralyzed and dampened by stroke, to go down after 20 years in the office. His party, FLN, has ruled Algeria since its independence from France in 1962. [NYT / Adam Nossiter]
- Protesters confronted the police on Monday when the authorities fired tear gas in crowds. In one case, the protesters set fire to a social insurance office. Young people say that the realm of Algeria's lucrative natural gas industry has not been shared and accused of Bouteflika's corruption regime. The president's health conditions often take him abroad for medical checks. he has not seen publicly since his battle in 2013. [Associated Press / Aomar Ouali]
- The move has given an international response. Paris showed solidarity with Algeria and French patriots gathered in Marseille and Toulouse. Demonstrators also gathered at Union Square in New York City and the San Francisco Civic Center on Sunday. Fear of repeating Algeria's cruel civil war in 1990 had discouraged protests against Bouteflika, so far. [Al Jazeera]
- The civil war followed Algeria's independence at the end of the century and has often been used as a political tool to deter citizens from pushing the government. Now younger generations who are facing high employment levels are ready for new leadership. [NPR / Shannon Van Sant]
- Political, military and business elites run Algeria in Bouteflika's name – and continue to support their regime to maintain their power. Bouteflika's campaign manager promised that the president would demand an early election if he were to win again on April 18, but the powerful coalition did not date the election. [Vox / Alex Ward]
- The best T-Mobile executives spent $ 195,000 at Trump's Washington hotel while merging with Sprint. The telecommunications giant acknowledged this in a letter to the Congress – and it still needs the approval of the FCC and Trump administration for the merger. [The Verge / Shannon Liao]
- Federal disaster money benefits rich people more than low-income people or minorities in America. The government is trying to minimize taxpayers' risk when allocating support, which means that wealthy people get more money and inequality worsened by disasters. [NPR / Rebecca Hersher and Robert Benincasa]
- 2020 Democratic Presidential Assembly Amy Klobuchar allegedly "shaded and prepared" by his staff. The accounts of the Minnesota Senator's leadership style have initiated a conversation about female rage. [Atlantic / Caitlin Flanagan]
- False news gets harder to track. As the White House faces accusations of working too closely with Fox News, the difference between political message and journalism is more confusing than ever. [Axios / Sara Fischer]
- Steve Bannon's plans for Europe have not yet taken flight – but Trump's former chief strategist is still optimistic about increasing far across the continent in a plan called the "movement". As the 2019 election in Europe near populist parties Distances themselves from the Americans. [Politico Europe / Maїa de la Baume and Silvia Sciorilli Borrelli]
"It is not my position to tell people how to feel, or their evil is invalid. But incidents such as these ask: where are the resolutions against homophobic statements? For anti-blackness? For xenophobia? Because a member says he will "send Obama home to Kenya?" " [ Rep. Alexandria Ocasio-Cortez (D-NY) on Twitter one day before the House voted on a resolution condemning anti-Semitism in response to rope. Ilhan Omar's comments on pro-Israel advocates ]
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