Home / Health / Trump-driven marketing of unproven coronavirus drug-generated spike in prescription, study finds

Trump-driven marketing of unproven coronavirus drug-generated spike in prescription, study finds



Advertising a small study of a potential covid-19 treatment was sufficient to create a 200 percent increase in hydroxychloroquine and chloroquine prescription in March. Although the largest plant was short-lived, nearly half a million extra prescriptions were filled during a ten-week period studied by researchers, according to results published yesterday in the Journal of the American Medical Association.

The national study found that hydroxychloroquine / chloroquine prescriptions increased slowly when the pandemic was explained, but postponed after publicity about a non-randomized study of 1

9 Chinese patients on March 17. Trump promoted the potential cure.

Increase in hydroxychloroquine and

chloroquine prescription

A study in the Journal of the American Medical Association measured the rise of hydroxychloroquine and chloroquine prescriptions as coronavirus pandemics grew in the United States and President Trump agreed to market the drug as a cure for covid-19.

percent Change

from weekly

prescription

during 2019

March 12th

WHO explains the coronavirus as a pandemic. The next day, the United States declares an emergency.

March 17

A Chinese study showing drug efficacy is being released and widely promoted on Fox News and by President Trump. Three days later, Trump embraces the drug at a press conference.

March 28

The FDA issues EUA to allow hydroxychloroquine and chloroquine used for some hospitalized patients. Three days later, the lack of the drug is reported.

April 24

The FDA warns against the use of hydroxychloroquine or chloroquine for COVID-19 outside hospitals.

Increase in hydroxychloroquine and

chloroquine prescription

A study in the Journal of the American Medical Association measured the rise of hydroxychloroquine and chloroquine prescriptions as coronavirus pandemics grew in the United States and President Trump agreed to market the drug as a cure for covid-19.

percent Change

from weekly

prescription

during 2019

March 12th

WHO explains the coronavirus as a pandemic. The next day, the United States declares an emergency.

March 17

A Chinese study showing drug efficacy is being released and widely promoted on Fox News and by President Trump. Three days later, Trump embraces the drug at a press conference.

March 28

The FDA issues EUA to allow hydroxychloroquine and chloroquine used for some hospitalized patients. Three days later, the lack of the drug is reported.

April 24

The FDA warns against the use of hydroxychloroquine or chloroquine for COVID-19 outside hospitals.

Increase of hydroxychloroquine and chloro-cooking recipes

A study in the Journal of the American Medical Association measured the rise of hydroxychloroquine and chloroquine prescriptions as coronavirus pandemics grew in the United States and President Trump agreed to market the drug as a cure for covid-19.

percent Change

from weekly

prescription

during 2019

March 12th

WHO explains the coronavirus as a pandemic. The next day, the United States declares an emergency.

March 17

A Chinese study showing drug efficacy is being released and widely promoted on Fox News and by President Trump. Three days later, Trump embraces the drug at a press conference.

March 28

The FDA issues EUA to allow hydroxychloroquine and chloroquine used for some hospitalized patients. Three days later, the lack of the drug is reported.

April 24

The FDA warns against the use of hydroxychloroquine or chloroquine for COVID-19 outside hospitals.

Increase of hydroxychloroquine and chloro-cooking recipes

A study in the Journal of the American Medical Association measured the rise of hydroxychloroquine and chloroquine prescriptions as coronavirus pandemics grew in the United States and President Trump agreed to market the drug as a cure for covid-19.

percent Change

from weekly

prescription

during 2019

March 12th

WHO explains the coronavirus as a pandemic. The next day, the United States declares an emergency.

March 17

A Chinese study showing drug efficacy is being released and widely promoted on Fox News and by President Trump. Three days later, Trump embraces the drug at a press conference.

March 28

The FDA issues EUA to allow hydroxychloroquine and chloroquine used for some hospitalized patients. Three days later, the lack of the drug is reported.

April 24

The FDA warns against the use of hydroxychloroquine or chloroquine for COVID-19 outside hospitals.

Increase of hydroxychloroquine and chloro-cooking recipes

A study in the Journal of the American Medical Association measured the rise of hydroxychloroquine and chloroquine prescriptions as coronavirus pandemics grew in the United States and President Trump agreed to market the drug as a cure for covid-19.

percent Change

from weekly

prescription

during 2019

March 12th

WHO explains the coronavirus as a pandemic. The next day, the United States declares an emergency.

March 17

A Chinese study showing drug efficacy is being released and widely promoted on Fox News and by President Trump. Three days later, Trump embraces the drug at a press conference.

March 28

The FDA issues EUA to allow hydroxychloroquine and chloroquine used for some hospitalized patients. Three days later, the lack of the drug is reported.

April 24

The FDA warns against the use of hydroxychloroquine or chloroquine for COVID-19 outside hospitals.

The week before publication, the prescriptions were 31 percent higher than normal, but over the next week, the prescriptions shot up 214 percent above normal, say researchers from Brigham and Women’s Hospital in Boston, the Boston Veteran’s Administration Healthcare System and GoodRx.

The number of short-term prescriptions increased much higher – from 2,208 prescriptions during one week last year to 45,858 this year – an increase of almost 2,000 percent. The increase in short-term prescriptions (up to 28 tablets) continued throughout the 10-week study, still up more than 800 percent near the end of April.

But the prescription for more than 60 tablets had dropped by two-thirds from a year earlier, a very dangerous sign that patients in need of drugs for the treatment of lupus or rheumatoid arthritis were struggling to get their normal medication because of reported drug shortages.

The study found that the most popular high blood pressure medications, losartan, amlodopine and lisinopril, remained relatively stable over the 10-week period despite concerns that they may increase the sensitivity to covid-19. High blood pressure is considered a risk factor for covid-19, but the drugs that treat it may contribute to that danger, so the researchers had expected the prescription amount to fall.

While most drug demand was lower,

recipes shortened for

hydroxychloroquine and

chloroquine under quarantine

Percentage change from weekly prescriptions 2019

Hydroxychloroquine

chloroquine

Hydrocodone-

paracetamol

While most drug demand was lower,

recipes shortened for

hydroxychloroquine and chloroquine

under quarantine

Percentage change from weekly prescriptions 2019

Hydroxychloroquine

chloroquine

Hydrocodone-

paracetamol

While most drug demand was down, prescriptions are prescribed

quarantine hydroxychloroquine and chloroquine

Percentage change from weekly prescriptions 2019

Hydroxychloroquine

chloroquine

Hydrocodone-

paracetamol

While most drug demand was down, prescriptions are prescribed

quarantine hydroxychloroquine and chloroquine

Percentage change from weekly prescriptions 2019

Hydroxychloroquine

chloroquine

Hydrocodone-

paracetamol

Another unexpected finding was the lack of a peak in prescription for azithromycin, which can treat bacterial infections and was used in early studies with hydroxychloroquine to treat covid-19. Although mentioned together with the other drugs, azithromycin did not attract as much attention and prescriptions for the drug fell rather than nailed.

Some of the most common prescriptions also declined this year compared to last year, the study found, including amoxicillin for routine infections and atorvastatin to lower cholesterol. They were both almost two-thirds. Researchers said that reductions may be due to patients losing insurance when they lose jobs or patients being unable to see a doctor to get a prescription during the pandemic.

The study was conducted with data from 58,332 stores and mail order pharmacies and then adjusted for national prices.


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