Prof Martin Gore, 67, one of Britain's leading cancer researchers, has died as a result of a yellow fever vaccination, the Royal Marsden NHS Trust has said.
Gore, who was widely respected for his work, was a professor of cancer medicine at the Cancer Research Institute and a consultant at Marsden.
Prince William, patron of Marsden, praised. "I have found Martin as the source of inspiration," he said, adding that Gore's passion for his work, and his apparent compassion and kindness for his patients, their family and friends, reinforce my knowledge that Royal Marsden is a truly special place. " 1
Senior researchers expressed their grief. Prof Peter Openshaw, a former British Society for Immunology, said Gore" was a leader in cancer biology and made a major contribution to research in this field and the treatment of thousands of patients. My thoughts are with his family, friends and colleagues. "Yellow fever vaccination certificates are required by some countries as a condition of entry. Deaths from vaccination were very rare, but there was a higher risk among the elderly," said Openshaw.
He said: "Yellow fever is a serious viral disease in the tropics and spread by mosquito bites. The yellow fever vaccine has been available for many years and several studies have been conducted in their safety and efficacy.
"While the overall risk of serious side effects is still very low (about one in 100,000 vaccine recipients) It appears that people over the age of 60 have a three to four-fold increased risk of experiencing these severe effects compared to younger people. however, based on very few reported side effects.
"This risk must be balanced against the risk of getting yellow fever if you travel to an infected area – a nasty disease with high mortality."  Openshaw added: "The NHS recommends that everyone over 60 years of talking to their doctor before receiving the vaccine, and the best way to avoid the serious complications that can follow yellow fever infection is not to travel to parts of the world that put you in danger. Yellow fever vaccine contained a live attenuated form of the virus, says Dr. Louisa James, a lecturer in immunology at Queen Mary University of London.
She said: "Yellow fever vaccine works by activating an immune response against the virus and this response can protect against infection for up to 10 years. Yellow fever vaccine is very effective and mass vaccination campaigns in the early 20th century led to the disease disappearing in many African countries.
"More than 600m doses of yellow fever vaccine have been worldwide and it is safe for the majority of individuals. Yellow fever vaccine can very rarely cause serious side effects, including life-threatening illness. People over 60 seem to have a slightly higher risk of having side effects from yellow fever vaccine but the risk is still extremely low.
"Vaccination is an important strategy for combating the devastating effect of yellow fever viruses that killed tens of thousands of people during recent outbreaks in Africa. "