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Intermittent fasting increases the life span of patients with cardiac catheterization

  Intermittent fasting increases the life span of cardiac catheterization patients
While intermittent fasting may sound like another diet, the practice of routinely not eating and drinking for short periods has again shown to lead to potentially better health outcomes. Credit: Intermountain Healthcare

While intermittent fasting may sound like another dieting diet, the practice of routinely not eating and drinking for short periods has once again proven to lead to potentially better health outcomes.

In a new study by researchers at the Intermountain Healthcare Heart Institute in Salt Lake City, researchers have found that patients with cardiac catheterization who practiced regular periodic fasting lived longer than patients who did not. In addition, the study found that patients who practice intermittent fasting are less likely to be diagnosed with heart failure.

"This is another example of how we find that regular fasting can lead to better health outcomes and longer life," said Benjamin Horne, Ph.D., lead investigator for the study and director of cardiovascular and genetic epidemiology at the Intermountain Healthcare Heart Institute .

Results of the study will be presented at the American Heart Association Scientific Sessions 201

9 in Philadelphia on Saturday, November 16, 2019.

In the study, researchers asked 2,001 Intermountain patients who underwent cardiac catheterization from 2013 to 2015 a series of lifestyle issues, including whether they routinely practiced fasting or not. Researchers then followed up with these patients 4.5 years later and found that routine fasting had greater survival than those who did not.

Because people who are routinely also known to engage in other healthy behaviors, the study also evaluated other parameters including demographics, socioeconomic factors, heart risk factors, comorbid diagnoses, medications and treatments, and other lifestyle behaviors such as smoking and alcohol consumption.

Correcting statistically for these factors, long-term routine fasting remained a strong predictor of better survival and lower risk of heart failure, according to researchers.

The Intermountain Healthcare Heart Institute has the opportunity to carefully study intermittent fasting because a large portion of its patients regularly do so: a significant portion of Utah's population belongs to the Church of Jesus Christ of Latter-day Saints, whose members usually fast on the first Sunday of the month through to go without food or drink for two consecutive meals and thus not eat for a day.

Although the study does not show that fasting is the causal effect for better survival, these real results in a large population suggest that fasting can have an effect and calls for further studies of the behavior.

"While many fast weight-loss diets are available today, the various purposes of fasting in these diets and in this study should not be confused with fasting," Dr. Horne said. "All proposed biological mechanisms for health benefits of solid derived from effects that occur during the fasting period or are consequences of fasting. "

Dr. Horne has previously conducted studies on the risk of diabetes and coronary artery disease in patients and found that the number is lower in patients who exercise routine fasting. These studies were published in 2008 and 2012 and suggested that The decades-long progression of chronic diseases can be enhanced by long-term routine fasting.

Why long-term intermittent fasting leads to better health outcomes is still largely unknown, but Dr. Horne said there may be a variety of factors. Fasting affects a person's levels of hemoglobin, red blood cells, human growth hormone and lowers sodium and bee arbonate levels, while activating ketosis and autophagy – all factors that lead to better heart health and specifically reduce the risk of heart failure and coronary heart disease

"With the lower risk of heart failure we found, which is consistent with previous mechanistic studies, this suggests study on routine fasting with a low frequency over two-thirds of life activates the same biological mechanisms that fasting diets are suggested to activate quickly, "Dr. Langhorne.

Scientists speculate that fasting routinely for a period of years and even decades condition the body to activate the beneficial mechanisms for fasting after a shorter period than usual.

It takes about 12 hours of fasting for the effects to be activated, but long-term routine fasting can shorten that time so that each routine Faster's daily evening / fasting period between dinner and breakfast provides a small amount of daily benefit, they noted.

Further studies are ongoing that will answer this question and other questions related to possible mechanisms for effects on the development of chronic disease and survival. Further research will also investigate potential psychological effects of fixed and potential effects on appetite and hunger perception.

Fasting is not for everyone. Researchers warn that pregnant and lactating women should not fast, as do young children and frail older adults. People who have had an organ transplant, who have a suppressed immune system, who experience acute or severe chronic infections, and those with eating disorders should also not fast.

People who have been diagnosed with chronic diseases – especially those who are taking medication for diabetes, blood pressure or heart disease – should not fast unless under the careful care and supervision of a physician because of the serious adverse effects that medications in combination with fasting can cause, including as hypoglycemia.

Mayo Clinic Minute: Intermittent Fixed Facts

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Intermountain Medical Center

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Intermittent fasting increases the life span of patients with cardiac catheterization (2019, November 16)
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