Aspirin is still one of the most widely used medications in the world, although it is no longer recommended as a prevention by many health authorities.
There is no evidence that low-dose aspirin – less than 325 milligrams per day – should be taken by most adults in good cardiovascular health, according to a new review of existing research published on Wednesday in the British Journal of Clinical Pharmacology.
The review, which focused on the risks and benefits of low-dose daily aspirin, found that the risk of a major bleeding event due to the drug’s thinning effects outweighs the benefits.
This latest analysis, which looked at 67 studies, found that low dose aspirin use in people without cardiovascular disease was associated with a 1
However, there was also a 47% higher risk of gastrointestinal bleeding and a 34% higher risk of skull bleeding.
“Our document confirms that there is no evidence to take aspirin in primary prevention, that is, in healthy people,” study authors Dr. Lee Smith, a reader in Physical Activity and Public Health at Anglia Ruskin University in the United Kingdom and Dr. Nicola Veronese, a geriatrician at the University of Palermo, Italy, said in an email.
The “take home” message in our paper is that a low dose of aspirin is (only) good when you already have a cardiovascular condition. “
“Low-dose aspirin is one of the most widely used medications in the world. In addition, our umbrella review suggests that the importance of the risks, especially bleeding, should not be considered secondary,” Smith and Veronese said.
Given the various interventions now available to prevent cardiovascular disease, such as statins, blood pressure medication, and helping to quit smoking and lose weight, the results of the research examined the use of aspirin as a preventative.